Ayurvedic medicine is a personalized system of traditional medicine native to India and the Indian subcontinent. It is based\non a holistic view of treatment which promotes and supports equilibrium in different aspects of human life: the body, mind,\nand soul. Popular Ayurvedic medicinal plants and formulations that are used to slow down brain aging and enhance memory\ninclude Ashwagandha (Withania somnifera), Turmeric (Curcuma longa), Brahmi (Bacopa monnieri), Shankhpushpi (Convolvulus\npluricaulis, Evolvulus alsinoides, and other species), gotu kola (Centella asiatica), and guggulu (Commiphora mukul and related\nspecies) and a formulation known as Br�¯ahm�¯�± Ghita, containing Brahmi, Vac�¯a (Acorus calamus), Kus.\nt.ha (Saussurea lappa),\nShankhpushpi, and Pur�¯an.a Ghita (old clarified butter/old ghee). The rationale for the utilization of Ayurvedic medicinal plants\nhas depended mostly on traditional usage, with little scientific data on signal transduction processes, efficacy, and safety. However,\nin recent years, pharmacological and toxicological studies have begun to be published and receive attention from scientists for\nverification of their claimed pharmacological and therapeutic effects. The purpose of this review is to outline the molecular\nmechanisms, signal transduction processes, and sites of action of some Ayurvedic medicinal plants. It is hoped that this description\ncan be further explored with modern scientific methods, to reveal new therapeutic leads and jump-start more studies on the use of\nAyurvedic medicine for prevention and treatment of dementia.
Loading....